The Planar Cell Polarity (PCP) signaling pathway governs cell movements that drive axis elongation and neural tube closure in vertebrate embryos, and certain vertebrate PCP proteins have also been implicated … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-a?rss=1">[Read more]</a>
Developmental processes can define repeated patterns of structure, such as somites in vertebrates. In plants, too, repeated structures arise during growth and development. As the above-ground shoot grows, it sends … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-b?rss=1">[Read more]</a>
In electronic circuitry, the band gap of a semi-conductor helps to provide the barrier that keeps charge carriers from flowing until a voltage is applied that switches the device. As … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-c?rss=1">[Read more]</a>
Among the first facts students learn about the natural world is that plants owe their green color to the pigment chlorophyll. There have actually been a handful of slightly different … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-d?rss=1">[Read more]</a>
Carbon nanotubes can function as chemical sensors by virtue of the shifts in resistance or capacitance induced when small molecules bind to their surfaces. Unfortunately, many molecules bind rather tightly, … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-e?rss=1">[Read more]</a>
Ion binding by proteins can exert a major influence on electron transfer events in biological systems. Park et al. (p. 1324) discovered an analogous phenomenon in a simpler synthetic system. … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-f?rss=1">[Read more]</a>
What would our climate future look like if we stopped building any new infrastructure that used fossil fuels? Davis et al. (p. 1330; see the Perspective by Hoffert) made the … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-g?rss=1">[Read more]</a>
In October 2010, the Convention on Biological Diversity will meet to assess the current condition of global biodiversity and to propose and agree on priorities for its future conservation. In … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1253-h?rss=1">[Read more]</a>
The ability to expand hematopoietic stem cells (HSCs) during ex-vivo culture has been an important goal for over 20 years. Using a high-throughput chemical screen, Boitano et al. (p. 1345, … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-a?rss=1">[Read more]</a>
Transient conformations are important to protein function; however, detecting and characterizing these states is technically challenging. Korzhnev et al. (p. 1312; see the Perspective by Al-Hashimi) combined recently developed methods … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-b?rss=1">[Read more]</a>
Efficient and accurate repair of double-strand DNA breaks is critical for genome stability and involves a process known as homologous recombination. During repair of the sheared ends, the DNA must … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-c?rss=1">[Read more]</a>
Many bacteria and archaea recognize invading viruses and plasmids. Foreign DNA is integrated into so-called clustered regularly interspaced short palindromic repeat (CRISPR) loci, and transcripts from these loci are processed … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-d?rss=1">[Read more]</a>
The growing appreciation that clinically abnormal behaviors in children and adolescents may be influenced or perhaps even initiated by developmental miscues has stoked an interest in mapping normal human brain … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-e?rss=1">[Read more]</a>
Theoretical studies have suggested that protons can be conducted rapidly in water trapped inside carbon nanotubes. C. Y. Lee et al. (p. 1320) connected two aqueous reservoirs with opened, single-walled … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-f?rss=1">[Read more]</a>
As a primary component of the martian atmosphere and as the primary greenhouse gas for Mars, carbon dioxide has played a role in climate and geological processes during martian history. … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-g?rss=1">[Read more]</a>
Filopodia are finger-like structures containing parallel bundles of actin filaments that are central to eukaryotic cell motility in a variety of contexts. K. Lee et al. (p. 1341) reconstituted filopodia-like … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-h?rss=1">[Read more]</a>
During their life cycle malaria parasites produce vast numbers of successive proliferative stages in their vertebrate hosts, and yet in the field most mosquitoes are free of parasites. Rodrigues et … <a href="http://www.sciencemag.org/cgi/content/full/329/5997/1255-i?rss=1">[Read more]</a>